THE AVENGERS versus THE SYMBIOTE
What If The Alien Costume had Possessed Spider-man? (Marvel comics)
Where: What if...? #4 When: October 1989
Why: Danny Fingeroth How: Mark Bagley
The story so far...
In our reality Peter Parker was able to free himself of the influence of the alien symbiote he obtained during the Secret Wars, but in another universe Peter Parker was not so fortunate.
Reed Richards was able to intervene and remove the symbiotic costume to contain it, but neither he nor Dr. Strange could prevent the creature escaping to again seek out the Spider-man once more.
The symbiote reemerges during a battle between Dr. Strange and Hulk, and wrenches the green goliath from being banished to another dimension. Combatting Strange and Hulk, the symbiote recognises an even more powerful host, and thus the incredible Hulk becomes the possessor of the black costume.
Leaving behind a frail and aged Peter Parker, the symbiote-Hulk now has the combined might of Peter Parker, Dr. Strange, Reed Richards, Black Cat and the Avengers in pirsuit of it. But will they survive long enough to stop it?
Full Article: http://secretearths.blogspot.com/2007/03/avengers-versus-symbiote-what-if-alien.html